GENOTOXICITY OF POLYSTYRENE (PS) MICROSPHERES IN SHORT-TERM EXPOSURE TO GAMETES OF THE SAND DOLLAR SCAPHECHINUS MIRABILIS (AGASSIZ, 1864) (ECHINODERMATA, ECHINOIDEA)

Microplastic pollution appears to be one of the major environmental problems in the world today, and researchers have been paying special attention to the study of the impact of microplastics on biota.In this article, we studied the short-term effects of polystyrene micro-spheres on genome integrity using the gametes of the Scaphechinus mirabilis s

Abstract Microglia dysfunction is implicated in several neurodegenerative disorders, including a rare microgliopathy; CSF1R-related adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (CSF1R-ALSP).CSF1R-ALSP is caused by heterozygous loss-of-function mutations in the colony stimulating factor 1 receptor (CSF1R) gene, which enco

Abstract Background In the vertebrate spinal cord, motor neurons (MN) are generated in stereotypical numbers from a pool of dedicated progenitors (pMN) whose number depends on signals that control their specification but also their proliferation and differentiation rates.Although the initial steps of pMN specification have been extensively studied,

Associations between selenium and cancer have directed attention to role of selenoproteins in the carcinogenic process.We used data from two population-based case-control studies of colon (n = 1555 cases, 1956 controls) and rectal (n = 754 cases, 959 controls) cancer.We evaluated the association between genetic variation in TXNRD1, TXNRD2, TXNRD3,

Wavevector anisotropy of ion-scale plasma turbulence is studied at various values of ion beta.Two complementary methods are used.One is Handheld Stick Vacuum multi-point measurements of magnetic field in the near-Earth solar wind as provided by the Cluster spacecraft mission, and the other is hybrid numerical simulation of two-dimensional plasma tu